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Esophageal manometry, pressure measurement

Esophageal manometry is the most effective method for assessing esophageal motility disorders.

The esophagus is a muscular, tube-shaped organ whose transport function is regulated by a complex nervous system. The most common symptoms of motility disorders include difficulty or pain when swallowing and episodic chest pain. Motility disorders may also contribute to gastroesophageal reflux disease. These disorders typically result from dysfunction of the nervous system, and occasionally from degeneration of muscle tissue. Gastroscopy and functional X-ray imaging of the esophagus often provide preliminary information about the nature of the motility disorder, but the most accurate method for evaluation is manometry. 

Common indications for esophageal manometry include: 

  • Eating-related problems (food or liquid sticking in the esophagus) 

  • Non-cardiac chest pain 

  • Unclear upper abdominal symptoms 

  • Evaluation of esophageal complications related to connective tissue diseases 

  • Preoperative assessment for reflux surgery 

  • Eating difficulties following surgical treatment (reflux surgery, bariatric surgery) 

  • Monitoring of diagnosed motility disorders and assessment of treatment effectiveness 

Watch the video: Esophageal manometry. Produced by HUS, with Finnish subtitles.

Discuss any potential medication pauses with your treating physician. Many common medications, such as those used for cardiovascular conditions, may affect esophageal motility to some extent, but pausing them is usually not necessary. However, medications specifically targeting esophageal function i.e. prokinetics should be discontinued two days before the examination. The same generally applies to strongly neuroactive medications, such as certain sedatives. 

Avoid alcohol for at least 36 hours before the examination. Try to get a good night's rest before the examination. Fast for at least 5 hours prior to the examination to prevent stomach contents from blocking the catheter or entering the airways during the examination. You may take necessary medications (excluding those affecting esophageal function) with a small amount of water. If you feel anxious about the procedure, you may bring a support person with you. 

A typical patient comment after the examination is: “I was worried for no reason.” 

The examination is performed by a physician with the assistance of a specially trained nurse. First, the nurse records your personal information into the device, reviews your preparation, and briefly explains the steps of the examination. The physician may then ask additional questions based on the referral and medical history.

Manometry cannot be performed under anesthesia, as your active participation is required during various stages. Sedatives are also avoided to prevent interference with esophageal motility. While not considered a pleasant examination, a Finnish study found that four out of five patients considered it less uncomfortable than gastroscopy. 

Catheter placement 

While seated, the physician inserts a semi-rigid catheter 3–4 mm in diameter through one of your nostrils. Before insertion, the nurse may lubricate your nostrils with oil drops. If the nostrils are very narrow, decongestant drops may be used. The catheter is treated with either lubricant or anesthetic gel—both are effective, but the lubricant has fewer side effects. Anesthetic spray may also be used, but it tastes unpleasant and inevitably flows into the throat. Nasal mucosa is sensitive, so irritation is difficult to avoid entirely. Occasionally, insertion or removal of the catheter may cause mild nosebleeds, which can be stopped by pinching the nose.

The tip of the catheter typically triggers a gag reflex in the lower throat. It is important not to panic at this stage and to follow the physician’s instructions carefully. By tucking your chin to your chest, the catheter is guided into the esophagus rather than the trachea. Swallowing small sips of water through a straw helps open the pathway to the esophagus. The physician then advances the catheter into the upper part of the stomach. The catheter is secured behind the head with a strap. The intensity and duration of throat irritation caused by the catheter vary. Some patients adapt immediately once the catheter is in place, while others experience nausea and gagging that subsides within a few minutes. 

Measurement procedure 

You will be asked to lie down for the measurement. The examination is usually performed in a supine position, but due to interference from heart rate and respiratory movements, a side position may sometimes be necessary. First, a baseline measurement is taken, during which a swallowing pause of 20–30 seconds calms the esophagus. Then, functional measurements begin, where you swallow a teaspoon of liquid (water or mild saline) from a syringe at least ten times. Finally, you sit up and drink a cup of liquid quickly. Additional measurements may be taken as needed, for example, while swallowing solid or liquid food.

The measurement typically lasts 10–15 minutes but may be significantly longer if, for example, strong gag reflexes interfere with the planned swallows. At the end, the nurse removes the catheter and the examination is complete. In some cases, the physician may provide an immediate preliminary assessment, but usually the measurement data must be analyzed further before results are available. 

If only esophageal manometry is performed, you may leave immediately after the examination and usually resume eating and drinking normally. If anesthetic was used, swallow carefully for the next couple of hours to avoid food entering the airway due to throat numbness. Common aftereffects include nasal pain or discharge and throat irritation. These are usually mild and resolve within a few hours, allowing you to return to your normal daily routine. 

After manometry, many patients undergo 24-hour monitoring of esophageal pH (acidity) or impedance (electrical resistance). 

The physician who referred you for the examination will inform you of the results and the next steps in your care. Contact your care unit if you do not have a scheduled appointment or call time.

Serious adverse effects are rarely associated with esophageal manometry, and the examination often provides clarity regarding long-standing and complex symptoms. 

Updated 10.11.2025